BREAKING NEWS – 27.05.2024

In a press release dated May 22, 2024, SolidWorld Group, the leading company in the fields of digital technologies, 3D printing, 3D biofabrication, and the production lines of next-generation photovoltaic panels, announced the filing of a patent for the first “advanced customization” of human tissue through the creation of specialized heads. These heads enable the replication of specific types of tissue, starting from the patient’s original cells. Electrospider, the globally patented 3D bioprinter by SolidWorld, developed in collaboration with the University of Pisa by its subsidiary Bio3DPrinting, is now capable, thanks to its new patented heads, of working with four different types of cells. These are specifically related to the reconstruction of tendons and myotendinous junctions (the critical transition points between muscles and tendons where muscle-generated tension is transmitted to the tendon). The machine can reproduce human cells and tissues, allowing the simultaneous printing of both the tissue support structure, made of biocompatible material through electrospinning with nanometric thickness, and the cell hydrogels containing various types of human cells. Layer by layer, the bioprinter creates portions of “living” human tissue from cells cultured in vitro, directly taken from the patient or donors, significantly reducing the waiting times for implantable material and the associated risks of rejection. This process also enables an in-depth analysis of samples for studies and research in various fields. Currently, Electrospider is used by healthcare institutions, hospitals, clinics, and research centers in Italy, the USA, Switzerland, and the Middle East. With this revolutionary patent, SolidWorld Group reaffirms its commitment to providing cutting-edge solutions for the creation of human tissues and organs to support medical research. Electrospider offers patients the possibility of avoiding numerous and painful transplant procedures, significantly reducing hospitalization times and consequently improving the operational methods of hospitals and healthcare facilities. The new Electrospider series introduces an innovative print head that allows the independent or synergistic use of five different biofabrication techniques in a single printing session. These techniques include electrospinning, pneumatic extrusion of standard, thermosensitive hydrogels (also containing cells), photocurable materials, and the extrusion of thermoplastic materials. Additionally, the print head integrates a pick-and-place device, facilitating the positioning and handling of supports for biological material culture during the bioprinting process. The design of the print head ensures simplicity, lightness, and reduced bulk, maximizing the efficiency of the bioprinting ecosystem. The activation mechanism of the technologies is designed to avoid the use of motors or components that could interfere with the electric field during electrospinning, ensuring reliability and reproducibility. This innovation represents a significant advancement in multiscale and multimaterial bioprinting. Bio3DPrinting thus establishes itself as a pioneer in providing cutting-edge solutions for the creation of complex biological constructs for regenerative medicine. The new print head greatly increases the versatility of the bioprinting ecosystem, expanding the range of printable materials from millimeter to nanometer scale. This brings the practical application of bioprinted constructs in clinical settings closer, advancing the goal of creating human organs from the patient’s cells. The patent filing confirms SolidWorld’s innovative approach and constant commitment to research. This achievement represents another significant progress in the company’s development plan, strengthening its position as a leader in the bioprinting and regenerative medicine sector. The statements in the press release reinforce our positive view on the stock; therefore, we confirm our recommendation: Target Price €7.00, Rating BUY, and Risk MEDIUM.

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